Natural dyes are derived from sources found in nature such as plants, insects, and minerals, while synthetic dyes are man-made chemicals produced in a laboratory. Natural dyes are typically more environmentally friendly as they are biodegradable and non-toxic, whereas synthetic dyes often contain harmful chemicals that can be damaging to the environment and human health. Additionally, natural dyes can produce unique and subtle color variations, while synthetic dyes offer a wider range of vibrant and consistent colors.