The best way to store USDC is by using a secure cryptocurrency wallet that supports the USDC token. Popular options include hardware wallets like Ledger or Trezor, or reputable software wallets like MetaMask or Trust Wallet. It is important to ensure that the wallet you choose is compatible with the Ethereum blockchain, as USDC is an ERC-20 token. Additionally, make sure to keep your private keys secure and consider enabling additional security measures such as two-factor authentication for added protection.