Yes, some pets have been known to detect illness in humans. For example, dogs have a remarkable sense of smell and can detect changes in a person's body odor when they are sick or have a medical condition. There have been instances where pets have alerted their owners to health issues such as seizures, cancer, or low blood sugar levels. However, it's important to note that while pets may be able to detect some illnesses, they are not a substitute for professional medical diagnosis and care.