Isshiki Otsutsuki's plan involves using the Ten-Tails to cultivate a Divine Tree in order to harvest chakra fruit and gain immense power. This plan would result in catastrophic consequences for the ninja world, as it would drain the world of its chakra, leading to widespread destruction and chaos. Additionally, the increase in power and abilities of Isshiki Otsutsuki would make him an unstoppable force, posing a significant threat to all ninja villages and their inhabitants.