The different locations on Hitogashima Island in "Ghost of Tsushima" hold significant roles in both the story and gameplay. For instance, Fort Sakai is where Jin's uncle, Lord Shimura, is imprisoned by the Mongols, emphasizing the theme of family and loyalty. Castle Shimura serves as Jin's family's ancestral home, providing a deep connection to his past and heritage. Areas like Kechi Fishing Village and Komatsu Forge offer diverse quests and side missions, enriching the gameplay experience while unveiling different aspects of the island's culture and history. Overall, each location adds depth to the immersive world of "Ghost of Tsushima" through its unique contributions to the narrative and gameplay.