The artwork and animation style of an anime play a crucial role in shaping the overall atmosphere of the series. The use of vibrant colors, detailed backgrounds, and fluid movements can evoke different emotions and enhance the storytelling experience for viewers. For example, bright and colorful animation styles may create a lighthearted and cheerful atmosphere, while dark and muted colors combined with a more gritty animation style can convey a sense of mystery or suspense. Overall, the artwork and animation style work together to set the tone, establish the setting, and immerse the audience in the world of the anime.