The characters in the series cope with the inevitability of fate and destiny by facing their challenges head-on, embracing their roles in the unfolding events, and finding inner strength to navigate the paths set before them. Some characters may struggle with accepting their destiny at first, but ultimately find peace and purpose in fulfilling their roles. Others may actively try to defy fate, leading to interesting plot developments and character growth. The series likely explores themes of free will, acceptance, and the power of choice in the face of predestined outcomes.