Friendship plays a significant role in the anime Tokyo Revengers as it is a central theme throughout the series. The bond between friends, loyalty, and camaraderie are showcased as characters work together to overcome challenges and protect each other. The protagonist, Takemichi, relies on his friends to support him and help him in his mission to change the future. The friendships in Tokyo Revengers not only provide emotional support but also drive the characters to grow and become better individuals.