Takemichi's relationship with his friends undergoes significant changes throughout the series. At the beginning, he has a somewhat distant and disconnected relationship with his friends from middle school. However, as Takemichi travels back in time and interacts with them more, their bond grows stronger, and they become more supportive and protective of each other. Over time, they become like a tight-knit family, willing to sacrifice and fight for each other. This transformation in their relationship showcases the power of friendship and loyalty in the face of challenges and adversity.