When you are asked to work on a project outside of your expertise, the best approach is to communicate openly with your team or supervisor. You can express your willingness to learn and contribute to the project while also highlighting your areas of expertise. It's important to seek guidance, training, or mentorship from colleagues who are more experienced in the task at hand. By being proactive, honest, and open to learning, you can effectively navigate the project and potentially acquire new skills and knowledge in the process.