The fame of the Mona Lisa has had a significant impact on tourism in Paris and the Louvre Museum. It has attracted millions of visitors from around the world who specifically come to see this iconic painting. The Louvre Museum experiences a surge in visitors due to the Mona Lisa's popularity, contributing to its status as one of the most visited museums globally. Additionally, the painting's fame has also boosted the overall tourism industry in Paris, as many tourists include a visit to the Louvre to see the Mona Lisa as a must-do activity during their trip to the city.