Light Yagami's manipulation of events in "Death Note" plays a crucial role in shaping the course of the series. By using the Death Note to eliminate criminals and those he deems as obstacles to his vision of creating a utopia, Light sets off a chain reaction of events that lead to a power struggle between him and L, the renowned detective trying to catch him. Light's manipulation not only impacts the lives of those around him but also drives the central conflict of the series, ultimately leading to a dramatic and intense conclusion.