Manipulation of information plays a crucial role in Light Yagami's strategies in the series "Death Note." Light uses his intelligence and strategic thinking to carefully manipulate information to achieve his goal of creating a new world order. By controlling how information is disseminated and perceived by others, Light is able to manipulate events, mislead his opponents, and maintain his facade of innocence. This manipulation of information allows Light to outwit his adversaries and stay one step ahead in his pursuit of power.