When handling a pet tarantula, it's important to approach them calmly and gently. Make sure your hands are clean and free of any strong scents that may startle them. Slowly scoop up the tarantula from the side or below, supporting its body gently but firmly. Avoid touching its abdomen or legs too much as they can be delicate. Always be cautious and aware of the tarantula's body language to ensure they are comfortable. It's recommended to limit handling to short periods to reduce stress on the tarantula.