Multi-party computation (MPC) enhances security in Bitcoin custody solutions by allowing multiple parties to jointly compute a function without revealing their individual inputs. In the context of Bitcoin custody, this means that no single party has access to the complete private key required to access the bitcoins. Instead, each party holds a share of the private key, and multiple parties must cooperate to perform transactions. This reduces the risk of a single point of failure or a single party absconding with the funds, thereby enhancing the overall security of the Bitcoin custody solution.