Yes, rabbits can be trained to use a litter box. It's best to start by placing the litter box in a corner of their enclosure where they naturally tend to go to the bathroom. You can gradually introduce them to the litter box by placing some of their droppings in it to help them associate it with the bathroom area. Additionally, using a litter that is safe for rabbits, such as paper-based or pelleted litter, can help encourage them to use the box. With patience and positive reinforcement, many rabbits can be successfully litter trained.