Lions adapt their hunting strategies when targeting larger prey like buffalo or giraffe by working together in coordinated groups called prides. When hunting larger prey, lions utilize teamwork to surround and isolate the target animal, often targeting the vulnerable young, sick, or elderly individuals within the herd. They also use their strength and agility to deliver coordinated attacks from different angles, aiming to bring down the large prey through overwhelming force and persistence. Additionally, lions may go for the throat or attempt to suffocate the larger prey to weaken them before delivering a fatal bite.