Yes, rabbits can be trained to use a litter box. They are naturally clean animals and can easily learn to use a litter box if properly trained. It's important to start the training early and be consistent with it. Place the litter box in a corner where the rabbit tends to go to the bathroom, use a litter that is safe for rabbits, and reward them with treats when they use the litter box correctly. With patience and positive reinforcement, most rabbits can be successfully litter box trained.