Staking USDC can generally be considered safe, as it is a stablecoin pegged to the value of the US dollar. However, it is essential to note that any form of staking or investment carries inherent risks, such as smart contract vulnerabilities, market fluctuations, and potential loss of funds. It's advisable to conduct thorough research, understand the staking platform, and assess the associated risks before proceeding with staking USDC.