Artists use the medium of sculpture to engage with physical space and form by manipulating three-dimensional space through the creation of physical objects. They can create sculptures that interact with the surrounding environment, altering the way viewers perceive and interact with the space. Sculptors also utilize various techniques such as scale, texture, composition, and material choice to evoke different emotional responses and convey their intended messages. Additionally, artists may incorporate negative space, light, and shadow to further enhance the sculptural experience and create a dynamic relationship between the artwork and its environment.