Pablo Escobar, the notorious Colombian drug lord, died on December 2, 1993. He was killed in a shootout with Colombian National Police on a rooftop in MedellĂn, Colombia. Escobar had been on the run for several months after escaping from La Catedral, a luxurious private prison he had built for himself. His death marked the end of his reign as one of the most powerful and infamous drug traffickers in history.