Yes, you can train a pet rabbit to use a litter box, similar to how you would train a cat. Rabbits are naturally clean animals and can be taught to use a designated area for their bathroom needs. It's best to start training your rabbit when they are young, and consistency is key. Provide a litter box filled with rabbit-safe litter, place some of their droppings in the litter box to encourage them to use it, and reward them with treats or praise when they do so. With patience and positive reinforcement, many rabbits can be successfully house trained.